PML/RARA
Alias/Synonym: AML , Acute Myeloid Leukemia
CPT Code: 88377
- Includes:
- PML/RARA
- Specimen Type, Preferred:
- Bone marrow aspirate
- Specimen Type, Alternate:
- Peripheral blood
- Sample Quantity, Preferred:
- 2-3 mL
- Sample Quantity, Minimum:
- >0.5 mL
- Transport Container:
- Green top (Sodium Heparin) tube
- Lavender top (EDTA) tube
- Transport Temperature:
- Room temperature
- Collection Instructions:
- If bone marrow is dry tap, submit 5-10mL peripheral blood.
- Specimen Stability:
- Room temperature: 7 day(s)
- Rejection Criteria:
- Frozen
- Clotted
- Clinical Significance:
- Detects translocations involving PML and RARA.
- Limitations:
- FISH can only detect aberrations specifically targeted by probe used.
- Turnaround Time:
- 3 day(s)
- Reference Ranges:
- Quantitative analysis : cutoff value %