Pathline provides PCR COVID-19 Testing. Accurate results with Industry Leading turnaround times.

NextGen Sequencing HotSpot Cancer Panel

Alias/Synonym: NGS Hotspot

CPT Code: 81450

Includes:
ABL1, AKT1, ALK, APC, ATM, BRAF, CDH1, CDKN2A, CSF1R, CTNNB1, EGFR, ERBB2, ERBB4, EZH2, FBXW7, FGFR1, FGFR2, FGFR3, FLT3, GNA11, GNAQ, GNAS, HNF1A, HRAS, IDH1, IDH2, JAK2, JAK3, KDR, KIT, KRAS, MET, MLH1, MPL, NOTCH1, NPM1, NRAS, PDGFRA, PIK3CA, PTEN, PTPN11, RB1, RET, SMAD4, SMARCB1, SMO, SRC, STK11, TP53, VHL
Specimen Type, Preferred:
Formalin fixed paraffin embedded tissue
Specimen Type, Alternate:
Sample Quantity, Preferred:
1 Block
8 Slides
Sample Quantity, Minimum:
1 Block
5 Slides
Transport Container:
Paraffin block
Unstained slides
Transport Temperature:
Room temperature
Collection Instructions:
Charged slides should be cut at 4-5 microns thick.
Specimen Stability:
Room temperature: Indefinite
Rejection Criteria:
Frozen
Clinical Significance:
Comprehensive test that detects common hotspot mutations related to numerous cancer types.
Limitations:
This test is designed to detect gene mutations only. It is not intended to detect copy number changes or gene rearrangements.
Turnaround Time:
10-14 day(s)
Reference Ranges:
Cutoff value % based on assay sensitivity
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