Myeloperoxidase

Alias/Synonym: MPO

CPT Code: 88342

Includes:

Specimen Type, Preferred:

Formalin fixed paraffin embedded tissue

Specimen Type, Alternate:

Sample Quantity, Preferred:

1 block

2 slides

Sample Quantity, Minimum:

N/A

Transport Container:

Paraffin block

Unstained slides

Transport Temperature:

Room temperature

Collection Instructions:

Block and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.

Slides should be positively charged and cut at 3-4 microns for each stain/antibody ordered.

Specimen Stability:

N/A

Rejection Criteria:

No liquid specimens.

Uncharged slides

Clinical Significance:

Myeloperoxidase is a lysosomal enzyme found in myeloid cells, which metabolizes most of the hydrogen peroxide generated by activated phagocytes. Myeloperoxidase is reported to be expressed in neutrophils and monocytes in blood, in precursors of granulocytes in the bone marrow and in Kupffer cells of the liver. It is useful for the characterization of acute myeloid leukemia.

Limitations:

Turnaround Time:

1 day(s)

Reference Ranges:

N/A

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