NOTICE:  We are taking immediate action to address the global IT outage that occurred this morning and working as quickly as possible to restore the full functionality of our systems.  Depending on the length of the interruption, there may be a delay in our normal service times.   We appreciate your patience as we work to restore normal operations and will update you as we know more.

MYD88 L265P mutation

Alias/Synonym:

CPT Code: 81305

Includes:
Myeloid Differentiation Primary Response 88
Specimen Type, Preferred:
Bone marrow aspirate
Specimen Type, Alternate:
Peripheral blood
Sample Quantity, Preferred:
2mL
Sample Quantity, Minimum:
0.5mL
Transport Container:
Lavender top (EDTA) tube
Green top (Sodium Heparin) tube
Transport Temperature:
Refrigerated
Collection Instructions:
If bone marrow is dry tap, submit 5-10mL peripheral blood.
Specimen Stability:
Room temperature: 2 day(s)
Refrigerated: 3 day(s)
Rejection Criteria:
Room temperature Frozen
Clotted
Clinical Significance:
Detects the L265P mutation in the MYD88 gene for Waldenstrom macroglobulinemia.
Limitations:
This test is designed to detect gene mutations only. It is not intended to detect copy number changes or gene rearrangements.
Turnaround Time:
10-14 day(s)
Reference Ranges:
Cutoff value % based on assay sensitivity