H. pylori
Alias/Synonym: H.pylori Bacteria
CPT Code: 88342
- Includes:
- Specimen Type, Preferred:
- Formalin fixed paraffin embedded tissue
- Specimen Type, Alternate:
- Sample Quantity, Preferred:
- 1 block
- 2 slides
- Sample Quantity, Minimum:
- N/A
- Transport Container:
- Paraffin block
- Unstained slides
- Transport Temperature:
- Room temperature
- Collection Instructions:
- Block and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.
- Slides should be positively charged and cut at 3-4 microns for each stain/antibody ordered.
- Specimen Stability:
- N/A
- Rejection Criteria:
- No liquid specimens.
- Uncharged slides
- Clinical Significance:
- Helicobacter pylori is strongly associated with inflammation of the stomach and is also implicated in the development of gastric malignancy, peptic ulcers, and gastric lymphomas in humans. Helicobacter pylori can exist in a number of locations: in the mucus, attached to epithelial cells, or inside of vacuoles in epithelial cells, where it produces adhesions that bind to membrane-associated lipids and carbohydrates in or on epithelial cells. The most reliable method for detecting H. pylori infection is a biopsy during endoscopy histologic examination and detection by immunohistochemistry. Immunohistochemical staining of H. pylori on the surface of gastric mucosa is a valuable tool for identification of H. pylori infections.
- Limitations:
- Turnaround Time:
- 1 day(s)
- Reference Ranges:
- N/A