GCDFP15
Alias/Synonym: Gross Cystic Disease Fluid Protein-15, Breast, Salivary Gland and Skin
CPT Code: 88342
- Includes:
- Specimen Type, Preferred:
- Formalin fixed paraffin embedded tissue
- Specimen Type, Alternate:
- Sample Quantity, Preferred:
- 1 block
- 2 slides
- Sample Quantity, Minimum:
- N/A
- Transport Container:
- Paraffin block
- Unstained slides
- Transport Temperature:
- Room temperature
- Collection Instructions:
- Block and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.
- Slides should be positively charged and cut at 3-4 microns for each stain/antibody ordered.
- Specimen Stability:
- N/A
- Rejection Criteria:
- No liquid specimens.
- Uncharged slides
- Clinical Significance:
- GCDFP is a prolactin-induced, secretory, actin-binding cytoplasmic protein, primarily produced by breast apocrine cells. GCDFP15 has been demonstrated in apocrine epithelia, lacrimal, ceruminous and Moll's glands and in numerous serous cells of the submandibular, tracheal, bronchial, sublingual and minor salivary glands. It can be detected at least focally in approximately 50-75% of breast carcinomas. It is frequently expressed in mammary and extramammary Paget's disease, apocrine sweat gland tumors and salivary gland tumors.
- Limitations:
- Turnaround Time:
- 1 day(s)
- Reference Ranges:
- N/A