FLT3 Mutation Analysis
Alias/Synonym:
CPT Code: 81245, 81246
- Includes:
- Specimen Type, Preferred:
- Bone marrow aspirate
- Specimen Type, Alternate:
- Peripheral blood
- Sample Quantity, Preferred:
- 2mL
- Sample Quantity, Minimum:
- 0.5mL
- Transport Container:
- Lavender top (EDTA) tube
- Green top (Sodium Heparin) tube
- Transport Temperature:
- Refrigerated
- Collection Instructions:
- If bone marrow is dry tap, submit 5-10mL peripheral blood.
- Specimen Stability:
- Room temperature: 2 day(s)
- Refrigerated: 3 day(s)
- Rejection Criteria:
- Room temperature Frozen
- Clotted
- Clinical Significance:
- Detects internal tandem duplications (ITDs) and tyrosine kinase domain (TKD) mutations in the FLT3 gene.
- Limitations:
- This test is designed to detect gene mutations only. It is not intended to detect copy number changes or gene rearrangements.
- Turnaround Time:
- 10-14 day(s)
- Reference Ranges:
- Cutoff value % based on assay sensitivity