EGFR Mutation Analysis

Alias/Synonym: FDA Approved, T790M

CPT Code: 81235

Specimen Type, Preferred:
Formalin fixed paraffin embedded tissue
Specimen Type, Alternate:
Sample Quantity, Preferred:
1 Block
8 Slides
Sample Quantity, Minimum:
1 Block
5 Slides
Transport Container:
Unstained slides
Paraffin block
Transport Temperature:
Room temperature
Collection Instructions:
Charged slides should be cut at 4-5 microns thick.
Specimen Stability:
Room temperature: Indefinite
Rejection Criteria:
Clinical Significance:
Detects mutations at p.G719 in exon 18, exon 19 deletions, p.T790M, p.S768I and insertions in exon 20, and p.L858R and p.L861Q in exon 21 of the EGFR gene.
This test is designed to detect gene mutations only. It is not intended to detect copy number changes or gene rearrangements.
Turnaround Time:
7 - 10 day(s)
Reference Ranges:
Cutoff value % based on assay sensitivity