CK8/18
Alias/Synonym: Cytokeratin 8 and 18, Simple and Pseudostratified Epithelium, Carcinoma Subtype
CPT Code: 88342
- Includes:
- Specimen Type, Preferred:
- Formalin fixed paraffin embedded tissue
- Specimen Type, Alternate:
- Sample Quantity, Preferred:
- 1 block
- 2 slides
- Sample Quantity, Minimum:
- N/A
- Transport Container:
- Paraffin block
- Unstained slides
- Transport Temperature:
- Room temperature
- Collection Instructions:
- Block and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.
- Slides should be positively charged and cut at 3-4 microns for each stain/antibody ordered.
- Specimen Stability:
- N/A
- Rejection Criteria:
- No liquid specimens.
- Uncharged slides
- Clinical Significance:
- In normal tissues, cytokeratins 8 and 18 are reported to be expressed in all simple and glandular epithelium and in neoplastic tissues, they have been reported to be expressed in adenocarcinomas and most squamous cell carcinomas. They may also be seen in some sarcomas or mesothelioma. These cytokeratins are absent from keratinizing squamous carcinomas.
- Limitations:
- Turnaround Time:
- 1 day(s)
- Reference Ranges:
- N/A