Alias/Synonym: Leukocyte Common Antigen

CPT Code: 88342

Specimen Type, Preferred:
Formalin fixed paraffin embedded tissue
Specimen Type, Alternate:
Sample Quantity, Preferred:
1 block
2 slides
Sample Quantity, Minimum:
Transport Container:
Paraffin block
Unstained slides
Transport Temperature:
Room temperature
Collection Instructions:
Block and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.
Slides should be positively charged and cut at 3-4 microns for each stain/antibody ordered.
Specimen Stability:
Rejection Criteria:
No liquid specimens.
Uncharged slides
Clinical Significance:
CD45 (leukocyte common antigen) is a transmembrane glycoprotein expressed on most nucleated cells of hematopoietic origin, except megakaryocytes and plasma cells. Although present in most lymphomas, Reed-Sternberg cells in classic Hodgkin lymphoma are negative. The antibody is a useful aid for classification of neoplasms as being hematolymphoid in origin.
Turnaround Time:
1 day(s)
Reference Ranges: