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Calreticulin Mutation Analysis (CALR)

Alias/Synonym: CALR

CPT Code: 81219

Specimen Type, Preferred:
Bone marrow aspirate
Specimen Type, Alternate:
Peripheral blood
Sample Quantity, Preferred:
Sample Quantity, Minimum:
Transport Container:
Lavender top (EDTA) tube
Green top (Sodium Heparin) tube
Transport Temperature:
Collection Instructions:
If bone marrow is dry tap, submit 5-10mL peripheral blood.
Specimen Stability:
Room temperature: 2 day(s)
Refrigerated: 3 day(s)
Rejection Criteria:
Room temperature Frozen
Clinical Significance:
Detects mutations in exon 9 of the CALR gene in myeloproliferative neoplasms (MPNs).
This test is designed to detect gene mutations only. It is not intended to detect copy number changes or gene rearrangements.
Turnaround Time:
7 - 10 day(s)
Reference Ranges:
Cutoff value % based on assay sensitivity