NOTICE:  We are taking immediate action to address the global IT outage that occurred this morning and working as quickly as possible to restore the full functionality of our systems.  Depending on the length of the interruption, there may be a delay in our normal service times.   We appreciate your patience as we work to restore normal operations and will update you as we know more.


Alias/Synonym: Myoepithelial, Myofibroblastic, and Smooth Muscle Cells

CPT Code: 88342

Specimen Type, Preferred:
Formalin fixed paraffin embedded tissue
Specimen Type, Alternate:
Sample Quantity, Preferred:
1 block
2 slides
Sample Quantity, Minimum:
Transport Container:
Paraffin block
Unstained slides
Transport Temperature:
Room temperature
Collection Instructions:
Block and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.
Slides should be positively charged and cut at 3-4 microns for each stain/antibody ordered.
Specimen Stability:
Rejection Criteria:
No liquid specimens.
Uncharged slides
Clinical Significance:
Basic calponin (calponin-h1) is a 34 kD actin, tropomyosin and calmodulin binding protein thought to be involved in the regulation of smooth muscle contraction. Immunohistochemical expression can be identified in myoepithelial cells, myofibroblasts, and smooth muscle cells throughout the body, as well as in smooth muscle tumors. It is particularly useful in the evaluation of in situ vs. invasive breast carcinoma.
Turnaround Time:
1 day(s)
Reference Ranges: