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Acute Lymphoblastic Leukemia FISH Panel

Alias/Synonym: ALL, Acute Lymphoblastic Leukemia

CPT Code: 88377x6

BCR/ABL1, MLL, 7/7q, XCE 7/8, PDGFRa, PDGFRb
Specimen Type, Preferred:
Bone marrow aspirate
Specimen Type, Alternate:
Peripheral blood
Sample Quantity, Preferred:
2-3 mL
Sample Quantity, Minimum:
>0.5 mL
Transport Container:
Green top (Sodium Heparin) tube
Lavender top (EDTA) tube
Transport Temperature:
Room temperature
Collection Instructions:
If bone marrow is dry tap, submit 5-10mL peripheral blood.
Specimen Stability:
Room temperature: 7 day(s)
Rejection Criteria:
Clinical Significance:
Detects the most common recurrent genetic abnormalities in Acute Lymphoblastic Leukemia.
FISH can only detect aberrations specifically targeted by probe used.
Turnaround Time:
3 day(s)
Reference Ranges:
Quantitative analysis : cutoff value %