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Lymphoma Panel

Alias/Synonym: NHL , Non-Hodgkin Lymphoma

CPT Code: 88377x4

Includes:
IGH/CCND1, IGH/BCL2, MYC, BCL-6
Specimen Type, Preferred:
Bone marrow aspirate
Specimen Type, Alternate:
Peripheral blood
Formalin fixed paraffin embedded tissue
Sample Quantity, Preferred:
2-3 mL aspirate
4 slides
1 block
Sample Quantity, Minimum:
>0.5 mL
Transport Container:
Green top (Sodium Heparin) tube
Lavender top (EDTA) tube
Unstained slides
Paraffin block
Transport Temperature:
Room temperature
Collection Instructions:
If bone marrow is dry tap, submit 5-10mL peripheral blood.
Charged slides should be cut at 4-5 microns thick.
Specimen Stability:
Room temperature for tubes: 7 day(s)
Room temperature for slides or block: indefinite
Rejection Criteria:
Frozen
Clotted
Clinical Significance:
Detects the most common recurrent genetic abnormalities in Non-Hodgkin Lymphoma.
Limitations:
FISH can only detect aberrations specifically targeted by probe used.
Turnaround Time:
3 day(s)
Reference Ranges:
Quantitative analysis : cutoff value %
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