ER/PR
Alias/Synonym: Estrogen Receptor/Progesterone Receptor, PgR
CPT Code: 88360x2
- Includes:
- Specimen Type, Preferred:
- Formalin fixed paraffin embedded tissue
- Specimen Type, Alternate:
- Sample Quantity, Preferred:
- 1 block
- 2 slides per test
- Sample Quantity, Minimum:
- N/A
- Transport Container:
- Paraffin block
- Unstained slides
- Transport Temperature:
- Room temperature
- Collection Instructions:
- Block and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.
- Slides should be positively charged and cut at 3-4 microns for each stain/antibody ordered.
- Specimen Stability:
- N/A
- Rejection Criteria:
- No liquid specimens.
- Uncharged slides
- Clinical Significance:
- Estrogen Receptor (ER) and Progesterone Receptor (PR) are measured in breast cancer specimens according to ASCO/CAP recommendations, for both prognostic and therapeutic purposes. Receptor expression is detected by binding of monoclonal rabbit anti-ER antibody clone 6F11 by Leica and monoclonal mouse anti-PR antibody clone 16 by Leica. ER and PR status is determined by the percentage of stained tumor cells, according to ASCO/CAP guidelines.
- Limitations:
- Turnaround Time:
- 2 day(s)
- Reference Ranges:
- N/A