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ER/PR

Alias/Synonym: Estrogen Receptor/Progesterone Receptor, PgR

CPT Code: 88360x2

Includes:
Specimen Type, Preferred:
Formalin fixed paraffin embedded tissue
Specimen Type, Alternate:
Sample Quantity, Preferred:
1 block
2 slides per test
Sample Quantity, Minimum:
N/A
Transport Container:
Paraffin block
Unstained slides
Transport Temperature:
Room temperature
Collection Instructions:
Block and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.
Slides should be positively charged and cut at 3-4 microns for each stain/antibody ordered.
Specimen Stability:
N/A
Rejection Criteria:
No liquid specimens.
Uncharged slides
Clinical Significance:
Estrogen Receptor (ER) and Progesterone Receptor (PR) are measured in breast cancer specimens according to ASCO/CAP recommendations, for both prognostic and therapeutic purposes. Receptor expression is detected by binding of monoclonal rabbit anti-ER antibody clone 6F11 by Leica and monoclonal mouse anti-PR antibody clone 16 by Leica. ER and PR status is determined by the percentage of stained tumor cells, according to ASCO/CAP guidelines.
Limitations:
Turnaround Time:
2 day(s)
Reference Ranges:
N/A
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