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Chronic Myelogenous Leukemia

Alias/Synonym: CML BCR/ABL1

CPT Code: 88377

Includes:
BCR/ABL1
Specimen Type, Preferred:
Bone marrow aspirate
Specimen Type, Alternate:
Peripheral blood
Sample Quantity, Preferred:
2-3 mL bone marrow aspirate
5-10 mL whole blood
Sample Quantity, Minimum:
Transport Container:
Green top (Sodium Heparin) tube
Lavender top (EDTA) tube
Transport Temperature:
Room temperature
Collection Instructions:
If bone marrow is dry tap, submit 5-10mL peripheral blood.
Specimen Stability:
Room temperature: 7 day(s)
Rejection Criteria:
Frozen
Clotted
Clinical Significance:
Detects translocation involving BCR and ABL1.
Limitations:
FISH can only detect aberrations specifically targeted by probe used.
Turnaround Time:
3 day(s)
Reference Ranges:
Quantitative analysis : cutoff value %