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CD57

Alias/Synonym: NK Cells,T-cell Subset

CPT Code: 88342

Includes:
Specimen Type, Preferred:
Formalin fixed paraffin embedded tissue
Specimen Type, Alternate:
Sample Quantity, Preferred:
1 block
2 slides
Sample Quantity, Minimum:
N/A
Transport Container:
Paraffin block
Unstained slides
Transport Temperature:
Room temperature
Collection Instructions:
Block and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.
Slides should be positively charged and cut at 3-4 microns for each stain/antibody ordered.
Specimen Stability:
N/A
Rejection Criteria:
No liquid specimens.
Uncharged slides
Clinical Significance:
The CD57 glycoprotein, also known as HNK-1, is a glycoprotein involved with cell adhesion. It is found on a subset of mononuclear cells with natural killer activity and on neuroectodermal cells expressing myelin-associated glycoprotein. The marker is associated with NK cells, some hematopoietic tumors, and neuroendocrine tumors, and may help distinguish HGPIN from high grade urothelial carcinoma.
Limitations:
Turnaround Time:
1 day(s)
Reference Ranges:
N/A
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