CA-125
Alias/Synonym: Ovarian, Breast, Other Adenocarcinoma
CPT Code: 88342
- Includes:
- Specimen Type, Preferred:
- Formalin fixed paraffin embedded tissue
- Specimen Type, Alternate:
- Sample Quantity, Preferred:
- 1 block
- 2 slides
- Sample Quantity, Minimum:
- N/A
- Transport Container:
- Paraffin block
- Unstained slides
- Transport Temperature:
- Room temperature
- Collection Instructions:
- Block and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.
- Slides should be positively charged and cut at 3-4 microns for each stain/antibody ordered.
- Specimen Stability:
- N/A
- Rejection Criteria:
- No liquid specimens.
- Uncharged slides
- Clinical Significance:
- CA125 (Cancer antigen 125) is a glycoprotein coded by the MUC16 gene, found in variety of tumors, including ovary, cervix, endometrium, GI tract, breast and thyroid, as well as normal tissue such as fallopian tube. It is not very specific, and may also be seen in irritated, inflamed or neoplastic mesothelial cells, as well as epithelioid sarcoma and desmoplastic small round cell tumor (DSRCT).
- Limitations:
- Turnaround Time:
- 1 day(s)
- Reference Ranges:
- N/A