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CA-125

Alias/Synonym: Ovarian, Breast, Other Adenocarcinoma

CPT Code: 88342

Includes:
Specimen Type, Preferred:
Formalin fixed paraffin embedded tissue
Specimen Type, Alternate:
Sample Quantity, Preferred:
1 block
2 slides
Sample Quantity, Minimum:
N/A
Transport Container:
Paraffin block
Unstained slides
Transport Temperature:
Room temperature
Collection Instructions:
Block and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.
Slides should be positively charged and cut at 3-4 microns for each stain/antibody ordered.
Specimen Stability:
N/A
Rejection Criteria:
No liquid specimens.
Uncharged slides
Clinical Significance:
CA125 (Cancer antigen 125) is a glycoprotein coded by the MUC16 gene, found in variety of tumors, including ovary, cervix, endometrium, GI tract, breast and thyroid, as well as normal tissue such as fallopian tube. It is not very specific, and may also be seen in irritated, inflamed or neoplastic mesothelial cells, as well as epithelioid sarcoma and desmoplastic small round cell tumor (DSRCT).
Limitations:
Turnaround Time:
1 day(s)
Reference Ranges:
N/A
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