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BOB 1

Alias/Synonym: B-cell Lymphocyte Transcription Factor

CPT Code: 88342

Includes:
Specimen Type, Preferred:
Formalin fixed paraffin embedded tissue
Specimen Type, Alternate:
Sample Quantity, Preferred:
1 block
2 slides
Sample Quantity, Minimum:
N/A
Transport Container:
Paraffin block
Unstained slides
Transport Temperature:
Room temperature
Collection Instructions:
Block and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.
Slides should be positively charged and cut at 3-4 microns for each stain/antibody ordered.
Specimen Stability:
N/A
Rejection Criteria:
No liquid specimens.
Uncharged slides
Clinical Significance:
BOB.1 is a transcription factor required for antigen-dependent germinal center formation. BOB.1 expression is present in a variety of non Hodgkin lymphomas (germinal center origin, some mediastinal large B-cell lymphoma and T-cell lymphoma) and lymphocyte predominant Hodgkin lymphoma.
Limitations:
Turnaround Time:
1 day(s)
Reference Ranges:
N/A