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BCR-ABL Gene Rearrangement, Quantitative (IS)

Alias/Synonym: BCR-ABL (IS) Major, BCR-ABL Minor

CPT Code: 81206, 81207

Includes:
Specimen Type, Preferred:
Bone marrow aspirate
Specimen Type, Alternate:
Peripheral blood
Sample Quantity, Preferred:
2 mL
Sample Quantity, Minimum:
0.5mL
Transport Container:
Lavender to (EDTA) tube
Green top (Sodium Heparin) tube
Transport Temperature:
Refrigerated
Collection Instructions:
If bone marrow is dry tap, submit 5-10mL peripheral blood.
Specimen Stability:
Room temperature: 2 day(s)
Refrigerated: 3 day(s)
Rejection Criteria:
Room temperature
Clotted
Frozen
Clinical Significance:
Quantitative detection of translocations involving BCR and ABL in Chronic Myeloid Leukemia (CML) and Acute Lymphoblastic Leukemia (ALL).
Limitations:
This test is designed to detect only the translocation involving BCR and ABL.
Turnaround Time:
3-5 day(s)
Reference Ranges:
Cutoff value % based on assay sensitivity
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