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BCR-ABL Gene Rearrangement, Quantitative (IS)

Alias/Synonym: BCR-ABL (IS) Major, BCR-ABL Minor

CPT Code: 81206, 81207

Specimen Type, Preferred:
Bone marrow aspirate
Specimen Type, Alternate:
Peripheral blood
Sample Quantity, Preferred:
2 mL
Sample Quantity, Minimum:
Transport Container:
Lavender to (EDTA) tube
Green top (Sodium Heparin) tube
Transport Temperature:
Collection Instructions:
If bone marrow is dry tap, submit 5-10mL peripheral blood.
Specimen Stability:
Room temperature: 2 day(s)
Refrigerated: 3 day(s)
Rejection Criteria:
Room temperature
Clinical Significance:
Quantitative detection of translocations involving BCR and ABL in Chronic Myeloid Leukemia (CML) and Acute Lymphoblastic Leukemia (ALL).
This test is designed to detect only the translocation involving BCR and ABL.
Turnaround Time:
3-5 day(s)
Reference Ranges:
Cutoff value % based on assay sensitivity