BCR-ABL Gene Rearrangement, Quantitative (IS)
Alias/Synonym: BCR-ABL (IS) Major, BCR-ABL Minor
CPT Code: 81206, 81207
- Includes:
- Specimen Type, Preferred:
- Bone marrow aspirate
- Specimen Type, Alternate:
- Peripheral blood
- Sample Quantity, Preferred:
- 8 Slides
- Sample Quantity, Minimum:
- 0.5mL
- Transport Container:
- Paraffin block
- Transport Temperature:
- Refrigerated
- Collection Instructions:
- If bone marrow is dry tap, submit 5-10mL peripheral blood.
- Specimen Stability:
- Room temperature: 2 day(s)
- Refrigerated: 3 day(s)
- Rejection Criteria:
- Room temperature
- Clotted
- Frozen
- Clinical Significance:
- Quantitative detection of translocations involving BCR and ABL in Chronic Myeloid Leukemia (CML) and Acute Lymphoblastic Leukemia (ALL).
- Limitations:
- This test is designed to detect only the translocation involving BCR and ABL.
- Turnaround Time:
- 3-5 day(s)
- Reference Ranges:
- Cutoff value % based on assay sensitivity