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AE1/AE3

Alias/Synonym: Pankeratin Cocktail, Low and High Molecular Weights

CPT Code: 88342

Includes:
Specimen Type, Preferred:
Formalin fixed paraffin embedded tissue
Specimen Type, Alternate:
Sample Quantity, Preferred:
1 block
2 slides
Sample Quantity, Minimum:
N/A
Transport Container:
Paraffin block
Unstained slides
Transport Temperature:
Room temperature
Collection Instructions:
Block and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.
Slides should be positively charged and cut at 3-4 microns for each stain/antibody ordered.
Specimen Stability:
N/A
Rejection Criteria:
No liquid specimens.
Uncharged slides
Clinical Significance:
Cytokeratins are intermediate filaments, most commonly associated with epithelial cells and are used to detect and/or characterize a tumor as carcinoma, although they are also found in some non-epithelial cell types/tumor. Cytokeratin AE1/AE3 is a pankeratin containing a cocktail of cytokeratins 1-8, 10, 14-16 and 19, but does not include CK17 or CK18.
Limitations:
Turnaround Time:
1 day(s)
Reference Ranges:
N/A
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