Pathline Client Update: Hematopathology Services

ABL1 Kinase Domain

Alias/Synonym: ABL1

CPT Code: 81170

Includes:
Specimen Type, Preferred:
Bone marrow aspirate
Specimen Type, Alternate:
Peripheral blood
Sample Quantity, Preferred:
2mL
Sample Quantity, Minimum:
0.5mL
Transport Container:
Lavender top (EDTA) tube
Green top (Sodium Heparin) tube
Transport Temperature:
Refrigerated
Collection Instructions:
If bone marrow is dry tap, submit 5-10mL peripheral blood.
Specimen Stability:
Room temperature: 2 day(s)
Refrigerated: 3 day(s)
Rejection Criteria:
Room temperature
Clotted
Frozen
Clinical Significance:
Detection of mutations that correlate to resistance to kinase inhibitors in patients with Chronic Myeloid Leukemia (CML) and acute lymphoblastic leukemia with Philadelphia chromosomes.
Limitations:
This test is designed to detect only mutations within the ABL kinase domain.
Turnaround Time:
5-7 day(s)
Reference Ranges:
5%